What is the most painful condition in the world?

Asked by: Aubree Altenwerth  |  Last update: May 3, 2025
Score: 4.8/5 (25 votes)

CRPS is not a short-term pain that will heal in time. The most excruciating part is that the pain is long-term, and likely to be for life. In fact, CRPS is known as the world's most painful incurable condition.

What is the #1 most painful thing in the world?

20 most painful conditions
  • Sciatica. ...
  • Kidney stones. ...
  • Trigeminal neuralgia. ...
  • Endometriosis. ...
  • Gout. ...
  • Acute pancreatitis. ...
  • Stomach or peptic ulcer. Peptic ulcers are open sores that form in the lining inside the stomach. ...
  • Fibromyalgia. Fibromyalgia is a condition that causes pain all over the body (widespread musculoskeletal pain).

What's the most painful disorder?

It's not always easy to know if someone is struggling with a mental health problem or what you can do about it. What is the most painful mental illness? Many experts believe it's borderline personality disorder. In this article, we look at how borderline personality disorder affects people.

What is the world's most painful injury?

So Regan goes on to say that it's widely accepted that breaking your femur is the most horrific, painful injury there is.

What pain hurts the most?

6 Most Painful Medical Conditions
  • Back Pain. About 80 percent of the people suffering from back pain recover from it quickly, the other 20 percent may experience chronic back pain. ...
  • Post Surgical Pain. ...
  • Complex Regional Pain Syndrome. ...
  • Peripheral Neuropathy. ...
  • Kidney Stones. ...
  • Cluster Headaches.

Living With The World's Most Painful Disease | MSNBC

36 related questions found

What hurts more than giving birth?

Kidney stones deliver sharp, pinpoint discomfort, while childbirth pain is a more diffuse, all-encompassing sensation. It's vital to grasp that pain is an entirely personal journey, with each individual's perception and tolerance painting a unique picture.

What's the worst pain a human can feel?

The full list, in no particular order, is as follows:
  • Appendicitis.
  • Trigeminal neuralgia.
  • Acute pancreatitis.
  • Gout.
  • Endometriosis.
  • Stomach ulcer.
  • Fibromyalgia.
  • Pain after surgery.

What hurts human the most?

20 painful health conditions
  • Shingles.
  • Cluster headaches.
  • Frozen shoulder.
  • Broken bones.
  • Complex regional pain syndrome (CRPS)
  • Heart attack.
  • Slipped disc.
  • Sickle cell disease.

What is the deadliest bone to break?

Here are 10 of the worst bone fractures you could get.
  • Skull. ...
  • Wrist. ...
  • Hip. ...
  • Rib. ...
  • Ankle. ...
  • Pelvis. A fracture in the pelvis can be life-threatening, just like hip fractures. ...
  • Tailbone. A tailbone fracture can make life difficult, and there is no way to hold the fractured tailbone in place. ...
  • Elbow. A broken elbow is very painful.

What is the most fatal injury?

Unintentional injuries are the leading cause of death for Americans aged 1-44 years old. The leading causes of death for unintentional injury include: unintentional poisoning (e.g., drug overdoses), unintentional motor vehicle (m.v.) traffic, unintentional drowning, and unintentional falls.

What is the most painful pain disorder?

In fact, CRPS is known as the world's most painful incurable condition. In the United States, it is referred to as the “suicide disease” as it can lead sufferers to resort to suicide as the only means to escape the huge pain that they bear.

What's the worst disorder?

What Is the Hardest Mental Illness to Live With?
  • Schizophrenia.
  • Severe Bipolar Disorder.
  • Borderline Personality Disorder (BPD)
  • Major Depression and Treatment-Resistant Depression.
  • Obsessive-Compulsive Disorder (OCD)
  • Eating Disorders.
  • Post-Traumatic Stress Disorder (PTSD)
  • So, What is the hardest mental illness to live with?

How painful are shingles on a scale of 1 to 10?

“Shingles is extremely painful," Wigand-Bolling said. “On a scale from one to 10, most patients will say the pain ranges from six to 10.” Between 1 and 5 days after the first symptoms occur, a rash will develop in the affected area.

What is the deadliest pain?

Trigeminal neuralgia. Trigeminal neuralgia is a peripheral, excruciating pain in the face that can be triggered by a harmless activity, such as talking, chewing, wearing a mask or washing your face, explains Dr.

How painful is giving birth?

Yes, childbirth is painful. But it's manageable. In fact, nearly half of first-time moms (46 percent) said the pain they experienced with their first child was better than they expected, according to a nationwide survey commissioned by the American Society of Anesthesiologists (ASA) in honor of Mother's Day.

What is the hardest chronic illness to live with?

Here's a list of debilitating diseases that significantly change the lives of millions of people:
  1. Alzheimer's and Dementia.
  2. Amyotrophic Lateral Sclerosis (ALS) – Lou Gherig's Disease. ...
  3. Parkinson's Disease. ...
  4. Multiple Sclerosis (MS) ...
  5. Scleroderma. ...
  6. Cystic Fibrosis. ...
  7. Chronic Obstructive Pulminary Disease (COPD) ...
  8. Cerebral Palsy. ...

What is the most painful injury?

In the realm of most painful injuries, compound fractures deserve a mention. These fractures occur when a broken bone pierces through the skin. Not exclusive to sports. But they can happen during high-impact activities like football or motocross.

What's the rarest bone to break?

Hyoid bone fractures represent 0.002% of all fractures; they are rare because the hyoid bone is well-protected by its location in the neck behind the mandible and in front of the cervical spine, as well as its mobility.

What is the most painful break you can have?

The femur is often put at the top of the most painful bones to break. Your femur is the longest and strongest bone in your body, running from your hip to your knee. Given its importance, it's not surprising that breaking this bone is an incredibly painful experience, especially with the constant weight being put on it.

What's the most physically painful thing?

Kidney stones – Deposits of minerals in the kidneys that pass through the urethra, causing excruciating pain as they move. Appendicitis – inflammation or rupture of the appendix. Trigeminal neuralgia – Chronic pain in the nerves of the head and face. Acute pancreatitis – inflammation of the pancreas.

What hurts the earth the most?

15 Biggest Environmental Problems of 2025
  • Melting Ice Caps and Sea Level Rise. ...
  • Ocean Acidification. ...
  • Agriculture. ...
  • Soil Degradation. ...
  • Food and Water Insecurity. ...
  • Fast Fashion and Textile Waste. ...
  • Overfishing. ...
  • Cobalt Mining.

What is pain that is unbearable?

Pain is said to be at level 9 when it is excruciating, prevents you speaking and may even make you moan or cry out. Level 10 pain is unbearable. You will be bedridden and possibly even delirious.

What is the most painful headache in the world?

Our data suggest that cluster headache attacks are more painful than several disorders widely considered to have very severe pain.